Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps1-10-03 | Basic Thyroid Gland, Iodine & Autoimmunity Basic | ETA2023

Characterization of anti-thyroglobulin antibodies epitopes in patients with hashimoto’s thyroiditis in areas with normal and excessive iodine intake

Casula Mauro , Viola Nicola , Migliorucci Benedetta , Nagayama Yuji , Horie Ichiro , Kawakami Atsushi , Kameda Hiraku , Nakamura Akinobu , Atsumi Tatsuya , Kameda Hiraku , Brancatella Alessandro , Sgro Daniele , Tosatto Laura , Santini Ferruccio , Coscia Francesca , Latrofa Francesco

Introduction: An increase in dietary iodine uptake, from insufficient to borderline values, induces the unmasking of a hidden epitope on thyroglobulin (Tg). No data about the effect of an excessive iodine intake on the expression of Tg epitopes recognized by human TgAb are available.Objective: To compare the expression of TgAb epitopes in sera of Hashimoto’s thyroiditis (HT) patients from areas with adequate, slightly and markedly excessive iodine i...